Metabolite page

Showing information for HMDB0029751 ('naphthalene')

Metabolite information
HMDB ID	HMDB0029751
Synonyms	Albocarbon Anaemia Camphor tar Carcinogenic Carcinogenic agent Cellular membrane Contaminant Diarrhoea Digestion Faecal Faeces Fecal Flora Gramineae Lightheaded Moth balls Moth flakes Mothballs Naftalen Naftaleno Naftalina Naphtalene Naphtaline Naphthalen Naphthalin Naphthaline Naphthene Nasal Pollutant Pulmonary Stool Tar camphor Tolboxane Unsteady White tar
Chemical formula	C10H8
IUPAC name	naphthalene
CAS registry number	91-20-3
Monisotopic molecular weight	128.062600256
Chemical taxonomy
Super class	Benzenoids
Class	Naphthalenes
Sub class	–
Biological properties
Pahtways
Author-emphasized biomarker in the paper(s)

Lung cancer metabolomics studies that identify HMDB0029751 ('naphthalene')

Reference	Country	Specimen	Marker function	Participants (Case)						Participants (Control)
Reference	Country	Specimen	Marker function	Cancer type	Stage	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status	Type	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status
Musharraf et al. 2015	–	plasma	–	adenocarcinoma, squamous cell carcinoma, NSCLC, SCLC, lung cancer	I, II, III	96	–	–	–	healthy, COPD	384	–	–	–

Reference	Chromatography	Ion source	Positive/Negative mode	Mass analyzer	Identification level
Musharraf et al. 2015	GC	EI	–	triple quadrupole	–

Reference	Data processing software	Database search
Musharraf et al. 2015	Agilent Mass Hunter Qualitative Analysis, Mass Hunter	Wiley registry NIST 11, Fiehn RTL libraries

Differential analysis
Classification analysis

Reference	Difference method	Mean concentration (case)	Mean concentration (control)	Fold change (case/control)	P-value	FDR	VIP
Musharraf et al. 2015	one way ANOVA, Turkey’s honest Significance Difference	–	–	38.4119686460894	4.98e-23	–	–

Reference	Classification method	Cutoff value	AUROC 95%CI	Sensitivity (%)	Specificity (%)	Accuracy (%)
Musharraf et al. 2015	Hierarchical clustering, Partial Least Square Discrimination	–	–	96.2	92	93.1