Metabolite page

Showing information for HMDB0000087 ('dimethylamine')

Metabolite information
HMDB ID	HMDB0000087
Synonyms	Adult-onset diabetes Chronic renal disease Ckd Csf Cutaneous [related but nor necessarily exact synonym] Cytoplasma DMA Digestion Dimethylamine anhydrous Dimethylamine anhydrous [dot] Dimethylamine aqueous solution Dimethylamine hydrobromide Dimethylamine hydrochloride Dimethylamine nitrate Dimethylamine perchlorate Dimethylamine phosphate [3:1] Dimethylamine solution Dimethylamine sulfate Dimethylamine sulfate [1:1] Dimethylamine, conjugate acid Dimethylammonium chloride Dimethylammonium formate Faecal Faeces Fecal Flora Gramineae HNMe2 Me2nh N,N-Dimethylamine N-Methyl-methanamine N-Methylmethanamine N-Methylmethanamine [acd/name 4.0] Nephropathy Neuron Niddm Non-insulin-dependent diabetes mellitus Osmolosis agent Renal disease Skin contact Soy Soya Soya bean Soybean Stool Topical Transdermal
Chemical formula	C2H7N
IUPAC name	dimethylamine
CAS registry number	124-40-3
Monisotopic molecular weight	45.057849229
Chemical taxonomy
Super class	Organic nitrogen compounds
Class	Organonitrogen compounds
Sub class	Amines
Biological properties
Pahtways	Citalopram Action Pathway Citalopram Metabolism Pathway
Author-emphasized biomarker in the paper(s)

Lung cancer metabolomics studies that identify HMDB0000087 ('dimethylamine')

Reference	Country	Specimen	Marker function	Participants (Case)						Participants (Control)
Reference	Country	Specimen	Marker function	Cancer type	Stage	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status	Type	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status
Hao et al. 2016	–	serum	diagnosis	lung cancer	I, II, III, IV	25	15, 10	64 (42–77)	smoker, non-smoker	before vs. after treatment (radiation treatment)	–	–	–	smoker, non-smoker

Reference	Chromatography	Ion source	Positive/Negative mode	Mass analyzer	Identification level
Hao et al. 2016	–	–	–	NMR	–

Reference	Data processing software	Database search
Hao et al. 2016	Chenomx NMR Suite 7.1, Metabolite Detector	–

Differential analysis
Classification analysis

Reference	Difference method	Mean concentration (case)	Mean concentration (control)	Fold change (case/control)	P-value	FDR	VIP
Hao et al. 2016	OPLS-DA, CV-ANOVA	–	–	–	–	–	–

Reference	Classification method	Cutoff value	AUROC 95%CI	Sensitivity (%)	Specificity (%)	Accuracy (%)
Hao et al. 2016	–	–	–	–	–	–