Metabolite information |
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| Chemical formula | - |
| IUPAC name | - |
| CAS registry number | - |
| Monoisotopic molecular weight | - |
Chemical taxonomy |
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Biological properties |
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| Pathways |
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| Reference | Country | Specimen | Marker function | Participants (Case) | Participants (Control) | |||||||||
| Cancer type | Stage | Number | Gender (M,F) | Age mean (range) (M/F) | Smoking status | Type | Number | Gender (M,F) | Age mean (range) (M/F) | Smoking status | ||||
| Klupczynska et al. 2019 | Poland | serum | diagnosis | adenocarcinoma, squamous cell carcinoma | I | 20 | 11, 9 | 62 ± 5 | smoker, non-smoker | noncancerous lung diseases | 20 | 8, 16 | 63 ± 6 | smoker, non-smoker |
| Reference | Chromatography | Ion source | Positive/Negative mode | Mass analyzer | Identification level |
| Klupczynska et al. 2019 | flow infusion | – | – | QTRAP | MS/MS |
| Reference | Data processing software | Database search |
| Klupczynska et al. 2019 | Analyst | – |
| Reference | Difference method | Mean concentration (case) | Mean concentration (control) | Fold change (case/control) | P-value | FDR | VIP |
| Klupczynska et al. 2019 | Wilcoxon rank-sum test | 0.24 ± 0.09 | 0.15 ± 0.04 | 1.88 | 3.81e-03 | 0.05 | – |
| Reference | Classification method | Cutoff value | AUROC 95%CI | Sensitivity (%) | Specificity (%) | Accuracy (%) |
| Klupczynska et al. 2019 | ROC analysis | – | 0.80 (0.64-0.92) | – | – | – |