Metabolite information |
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| HMDB ID | HMDB0001843 |
| Synonyms |
1-Aminopropenal acetic acidAPAAN-(1-oxo-2-Propenyl)-glycineN-Acryloyl-glycine |
| Chemical formula | C5H7NO3 |
| IUPAC name | 2-(prop-2-enamido)acetic acid |
| CAS registry number | 24599-25-5 |
| Monoisotopic molecular weight | 129.042593095 |
Chemical taxonomy |
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| Super class | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Sub class | Amino acids, peptides, and analogues |
Biological properties |
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| Pathways (Pathway Details in HMDB) |
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| Reference | Country | Specimen | Marker function | Participants (Case) | Participants (Control) | |||||||||
| Cancer type | Stage | Number | Gender (M,F) | Age mean (range) (M/F) | Smoking status | Type | Number | Gender (M,F) | Age mean (range) (M/F) | Smoking status | ||||
| Wu et al. 2014 | China | urine | diagnosis | NSCLC | – | 20 | 10, 10 | 38-74 | – | healthy | 20 | 10, 10 | 35-66 | – |
| Reference | Chromatography | Ion source | Positive/Negative mode | Mass analyzer | Identification level |
| Wu et al. 2014 | LC | ESI | positive | Q-TOF | MS/MS |
| Reference | Data processing software | Database search |
| Wu et al. 2014 | MassLynx | HMDB, metlin, lipidmaps |
| Reference | Difference method | Mean concentration (case) | Mean concentration (control) | Fold change (case/control) | P-value | FDR | VIP |
| Wu et al. 2014 | OPLS-DA, student’s t-test | – | – | 1.43 | 2.92e-04 | – | 1.71 |
| Reference | Classification method | Cutoff value | AUROC 95%CI | Sensitivity (%) | Specificity (%) | Accuracy (%) |
| Wu et al. 2014 | ROC curve analysis | – | – | – | – | – |